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2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide

CAS No. 529493-92-3

2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide( 2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide )

Catalog No. M26875 CAS No. 529493-92-3

2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide
  • Note
    Research use only, not for human use.
  • Brief Description
    2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Nav1.8 channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    529493-92-3
  • Formula Weight
    411.201
  • Molecular Formula
    C14H19BrO9
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(=O)OCC1OC(Br)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hemme J Hijma, et al. A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective NaV1.8 Inhibitor, in Healthy Male Adults. Pain Med. 2021 Aug 6;22(8):1814-1826.
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